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Melanocortin Biology 2 min read Updated 9 July 2026

What Is PT-141?

PT-141

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PT-141

Research peptide · 10mg

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PT-141 is a synthetic peptide described in the scientific literature as an analogue of alpha-melanocyte-stimulating hormone (alpha-MSH). It is studied as a melanocortin receptor agonist.

Research interest centres on its interaction with the MC3R and MC4R receptors and the neuroendocrine signalling pathways associated with them.

Research Classification

Compound Name
PT-141
Category
Melanocortin Biology
Research Area
Melanocortin receptor & neuroendocrine signalling
Storage Conditions
Store at 2–8°C, protected from light

Biological Pathways

  • Melanocortin receptor agonism — PT-141 is studied as an agonist of the melanocortin receptor family.
  • MC3R and MC4R signalling — research focuses on these two central-nervous-system melanocortin receptors.
  • Neuroendocrine biology — the peptide is investigated within neuroendocrine signalling models.

Mechanism Of Interest

PT-141 is studied as a synthetic alpha-MSH analogue and melanocortin receptor agonist.

Research focuses on its interaction with the MC3R and MC4R receptors, two members of the melanocortin receptor family expressed in the central nervous system.

Receptor signalling research examines how melanocortin receptor agonism is initiated and integrated.

Neuroendocrine biology explores how melanocortin signalling is studied within controlled research settings.

Why Researchers Are Interested

  • It provides a research tool for studying MC3R and MC4R receptor activity.
  • The melanocortin system is an active area of neuroendocrine research.
  • It allows comparison between synthetic analogues and endogenous melanocortin signalling.

Areas Of Ongoing Research

Melanocortin receptor agonismMC3R and MC4R signallingNeuroendocrine biologyAlpha-MSH analogue research

Storage Information

  • Store lyophilised material at 2–8°C, protected from light and moisture.
  • Keep reconstituted material refrigerated and handle under standard laboratory conditions.
  • Minimise freeze–thaw cycles to preserve peptide integrity.

Frequently Asked Questions

Which receptors does PT-141 interact with?+

The literature describes it as a melanocortin receptor agonist studied at the MC3R and MC4R receptors.

What is neuroendocrine biology?+

It is the study of how the nervous and endocrine systems interact through signalling molecules. PT-141 is studied within this context.

How is PT-141 stored?+

Lyophilised peptide is typically stored at 2–8°C, protected from light, with freeze–thaw cycles minimised.

References

  • Melanocortin receptors MC3R and MC4R (review literature)

    Peer-reviewed receptor biology reviews (PubMed-indexed)

  • Alpha-MSH analogues and neuroendocrine signalling

    Published receptor pharmacology literature

  • Melanocortin receptor sequence records

    UniProt public database

References point to reputable, publicly available scientific literature and databases for educational context. They are provided for background reading only.

For laboratory research use only. Not for human or animal consumption.

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PT-141

Research peptide · 10mg · Research use only

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